Rank 1: Moon Presence

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The Moon Presence is considered to be the most powerful boss in Bloodborne. This Great One pulls all the strings and ensures that new hunters enter the Hunter’s Dream and participate in the hunt of the beasts.
Besides the beasts, other Great Ones are also her target, as the protagonist is sent to silence the offspring “Mergo” in his nightmare. However, she remains hidden, only revealing herself when the protagonist poses a threat to her.
Although the Moon Presence is not a talented fighter, she has an attack that can instantly kill any being, unless you are a budding Great One and on the verge of transforming yourself.
Since Bloodborne only has one offshoot and most powerful beings for the list possess their strengths in manipulating humans as well as reality, the weight of my judgment lies more on their actions and influence in the world rather than their pure combat prowess. However, it is different in Dark Souls 1, 2, and 3. There, there are powerful bosses who can grind their enemies to dust: The strongest bosses in Dark Souls 1, 2 and 3 according to lore in the power ranking