There are plenty of NPCs in Borderlands 3 aboard Sanctuary. They can’t really be harmed. However, Moxxi’s Slot Machine achieved the seemingly impossible.
This is what distinguishes the NPCs aboard Sanctuary: The mostly nameless population of Sanctuary is primarily busy standing around, sitting on crates, or often babbling nonsensically.

Unbeatable NPC gets too close to the machine
Actually no harm: In the community, the nameless NPCs in Sanctuary are rather mediocre in popularity. This is primarily because they tend to stand around immobile and block paths. Also, the endlessly repeated lines annoy some.
If an NPC is standing in the doorframe, it is extremely hard to get them out of the way. Because: The NPCs are basically unbeatable. They don’t take weapon damage, anyway.
NPC caught at the machine: However, the unbeatable NPCs seem to not be so invulnerable after all. At least they appear to have a major weakness: gambling.
Specifically, that of the player. It may happen that instead of a nice reward, you pull a sharp grenade from a machine. This also happened to reddit user “noretehs“. Thankfully, he was at a safe distance when the machine unexpectedly spat out a bomb instead of a lot of money. Unfortunately, this didn’t apply to a “Crimson Raider” standing around.
In the video, the seemingly impossible happens: The bomb goes off and pulverizes the NPC. He disappears in a reddish cloud of dust and remains gone. Thus, the only weakness of the NPCs is revealed – and it amuses the community: “He knew the risk,” comments “chipotles_my_life“. “He will come back, stronger than ever,” suspects “LeKramsch” – and is probably right.
Borderlands 3 offers plenty of curiosities. But also on the content side, things will continue to be entertaining soon:
